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CBMT-27. PROTEOMIC MAP OF GLIOMA BIOPSIES REVEALS FUNCTIONAL DEFECTS IN ENDOCYTOSIS

BACKGROUND: Decades of molecular genetic analyses have shown that gliomas accumulate genetic alterations that result in the enhanced activity of growth factor receptor tyrosine kinases (RTKs) and mediators of downstream pathways. Among them are gain-of-function of EGFR, PDGFR, PIK3CAor BRAF, and los...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Boulay, Jean-Louis, Ritz, Marie-Françoise, Hutter, Gregor, Tostado, Cristobal, Buser, Dominik, Spiess, Martin, Frank, Stephan, Jenö, Paul, Mariani, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217094/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.146
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