CBMT-27. PROTEOMIC MAP OF GLIOMA BIOPSIES REVEALS FUNCTIONAL DEFECTS IN ENDOCYTOSIS

BACKGROUND: Decades of molecular genetic analyses have shown that gliomas accumulate genetic alterations that result in the enhanced activity of growth factor receptor tyrosine kinases (RTKs) and mediators of downstream pathways. Among them are gain-of-function of EGFR, PDGFR, PIK3CAor BRAF, and los...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Boulay, Jean-Louis, Ritz, Marie-Françoise, Hutter, Gregor, Tostado, Cristobal, Buser, Dominik, Spiess, Martin, Frank, Stephan, Jenö, Paul, Mariani, Luigi
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
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Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217094/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.146
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