Sonodynamic therapy-induced foam cells apoptosis activates the phagocytic PPARγ-LXRα-ABCA1/ABCG1 pathway and promotes cholesterol efflux in advanced plaque

In advanced atherosclerotic plaques, defective efferocytosis of apoptotic foam cells and decreased cholesterol efflux contribute to lesion progression. In our previous study, we demonstrated that 5-aminolevulinic acid (ALA)-mediated sonodynamic therapy (SDT) could induce foam cells apoptosis via the...

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Dades bibliogràfiques
Publicat a:Theranostics
Autors principals: Wang, Huan, Yang, Yang, Sun, Xin, Tian, Fang, Guo, Shuyuan, Wang, Wei, Tian, Zhen, Jin, Hong, Zhang, Zhiguo, Tian, Ye
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217053/
https://ncbi.nlm.nih.gov/pubmed/30429880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.26193
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