Allicin induces the upregulation of ABCA1 expression via PPARγ/LXRα signaling in THP-1 macrophage-derived foam cells

Allicin is considered anti-atherosclerotic due to its antioxidant and anti-inflammatory effects, which makes it an important drug for the prevention and treatment of atherosclerosis. However, the effects of allicin on foam cells are unclear. Thus, in this study, we examined the effects of allicin on...

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Veröffentlicht in:Int J Mol Med
Hauptverfasser: Lin, Xiao-Long, Hu, Hui-Jun, Liu, Yuan-Bo, Hu, Xue-Mei, Fan, Xiao-Juan, Zou, Wei-Wen, Pan, Yong-Quan, Zhou, Wen-Quan, Peng, Min-Wen, Gu, Cai-Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2017
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428973/
https://ncbi.nlm.nih.gov/pubmed/28440421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.2949
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