Lipoxin A4 promotes ABCA1 expression and cholesterol efflux through the LXRα signaling pathway in THP-1 macrophage-derived foam cells

Adenosine triphosphate-binding cassette transporter A1 (ABCA1) is a crucial cholesterol transporter and plays a central role in the high density lipoproteins (HDL) cholesterol metabolism and lipid clearance from the foam cell. Lipoxin A4 (LXA4) is an endogenous lipid mediator that requires cell-cell...

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Bibliografiske detaljer
Udgivet i:Int J Clin Exp Pathol
Main Authors: Sha, Yan-Hua, Hu, Yan-Wei, Gao, Ji-Juan, Wang, Yan-Chao, Ma, Xin, Qiu, Yu-Rong, Li, Shu-Fen, Zhao, Jia-Yi, Huang, Chuan, Zhao, Jing-Jing, Lu, Jing-Bo, Kang, Chun-Min, Zheng, Lei, Wang, Qian
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2015
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525887/
https://ncbi.nlm.nih.gov/pubmed/26261553
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