Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP‐1‐derived macrophages

1. SCOPE: Increased macrophage cholesterol efflux (ChE) is considered to have anti‐atherosclerotic effect counteracting cardiovascular disease. The principle pungent ingredient of the fruits of Piper nigrum, piperine, is identified in this study as a ChE inducer in THP‐1‐derived macrophages, and mec...

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Vydáno v:Mol Nutr Food Res
Hlavní autoři: Wang, Limei, Palme, Veronika, Rotter, Susanne, Schilcher, Nicole, Cukaj, Malsor, Wang, Dongdong, Ladurner, Angela, Heiss, Elke H., Stangl, Herbert, Dirsch, Verena M., Atanasov, Atanas G.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382977/
https://ncbi.nlm.nih.gov/pubmed/27862930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201500960
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