Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP‐1‐derived macrophages

1. SCOPE: Increased macrophage cholesterol efflux (ChE) is considered to have anti‐atherosclerotic effect counteracting cardiovascular disease. The principle pungent ingredient of the fruits of Piper nigrum, piperine, is identified in this study as a ChE inducer in THP‐1‐derived macrophages, and mec...

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Dades bibliogràfiques
Publicat a:Mol Nutr Food Res
Autors principals: Wang, Limei, Palme, Veronika, Rotter, Susanne, Schilcher, Nicole, Cukaj, Malsor, Wang, Dongdong, Ladurner, Angela, Heiss, Elke H., Stangl, Herbert, Dirsch, Verena M., Atanasov, Atanas G.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382977/
https://ncbi.nlm.nih.gov/pubmed/27862930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201500960
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