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Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP‐1‐derived macrophages

1. SCOPE: Increased macrophage cholesterol efflux (ChE) is considered to have anti‐atherosclerotic effect counteracting cardiovascular disease. The principle pungent ingredient of the fruits of Piper nigrum, piperine, is identified in this study as a ChE inducer in THP‐1‐derived macrophages, and mec...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Nutr Food Res
Prif Awduron: Wang, Limei, Palme, Veronika, Rotter, Susanne, Schilcher, Nicole, Cukaj, Malsor, Wang, Dongdong, Ladurner, Angela, Heiss, Elke H., Stangl, Herbert, Dirsch, Verena M., Atanasov, Atanas G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382977/
https://ncbi.nlm.nih.gov/pubmed/27862930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201500960
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