Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP‐1‐derived macrophages

1. SCOPE: Increased macrophage cholesterol efflux (ChE) is considered to have anti‐atherosclerotic effect counteracting cardiovascular disease. The principle pungent ingredient of the fruits of Piper nigrum, piperine, is identified in this study as a ChE inducer in THP‐1‐derived macrophages, and mec...

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Dettagli Bibliografici
Pubblicato in:Mol Nutr Food Res
Autori principali: Wang, Limei, Palme, Veronika, Rotter, Susanne, Schilcher, Nicole, Cukaj, Malsor, Wang, Dongdong, Ladurner, Angela, Heiss, Elke H., Stangl, Herbert, Dirsch, Verena M., Atanasov, Atanas G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382977/
https://ncbi.nlm.nih.gov/pubmed/27862930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201500960
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