Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP‐1‐derived macrophages

1. SCOPE: Increased macrophage cholesterol efflux (ChE) is considered to have anti‐atherosclerotic effect counteracting cardiovascular disease. The principle pungent ingredient of the fruits of Piper nigrum, piperine, is identified in this study as a ChE inducer in THP‐1‐derived macrophages, and mec...

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Detalhes bibliográficos
Publicado no:Mol Nutr Food Res
Main Authors: Wang, Limei, Palme, Veronika, Rotter, Susanne, Schilcher, Nicole, Cukaj, Malsor, Wang, Dongdong, Ladurner, Angela, Heiss, Elke H., Stangl, Herbert, Dirsch, Verena M., Atanasov, Atanas G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382977/
https://ncbi.nlm.nih.gov/pubmed/27862930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201500960
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