Erythrodiol, an Olive Oil Constituent, Increases the Half-Life of ABCA1 and Enhances Cholesterol Efflux from THP-1-Derived Macrophages

Cholesterol efflux (ChE) from macrophages is an initial step of reverse cholesterol transport (RCT). The ATP-binding cassette transporter A1 (ABCA1) is a key transporter for ChE and its increased expression is regarded to attenuate atherosclerosis. Thus, the identification and characterization of mo...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Wang, Limei, Wesemann, Sarah, Krenn, Liselotte, Ladurner, Angela, Heiss, Elke H., Dirsch, Verena M., Atanasov, Atanas G.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468437/
https://ncbi.nlm.nih.gov/pubmed/28659806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00375
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