Novel interactomics approach identifies ABCA1 as direct target of evodiamine, which increases macrophage cholesterol efflux

Evodiamine, a bioactive alkaloid from the fruits of the traditional Chinese medicine Evodia rutaecarpa (Juss.) Benth. (Fructus Evodiae, Wuzhuyu), recently gained attention as a dietary supplement for weight loss and optimization of lipid metabolism. In light of its use by patients and consumers, the...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Wang, Limei, Eftekhari, Pierre, Schachner, Daniel, Ignatova, Irena D., Palme, Veronika, Schilcher, Nicole, Ladurner, Angela, Heiss, Elke H., Stangl, Herbert, Dirsch, Verena M., Atanasov, Atanas G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056500/
https://ncbi.nlm.nih.gov/pubmed/30038271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29281-1
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