CADD-26. SMALL MOLECULE EPIGENETIC TARGETING OF METHYL-CPG BINDING PROTEIN 2 (MBD2) FOR MEDULLOBLASTOMA THERAPY

Adhesion G-protein coupled receptors (ADGRs) are transmembrane proteins involved in cell-cell/matrix interactions. We found that the ADGRB1 gene, which encodes Brain-specific angiogenesis inhibitor 1 (BAI1), is epigenetically silenced in human medulloblastomas through a methyl-CpG binding protein 2...

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發表在:Neuro Oncol
Main Authors: Van Meir, Erwin, Olson, Jeffrey, Zhu, Dan, Osuka, Satoru, Zhang, Zhaobin
格式: Artigo
語言:Inglês
出版: Oxford University Press 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216844/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1167
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