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CADD-26. SMALL MOLECULE EPIGENETIC TARGETING OF METHYL-CPG BINDING PROTEIN 2 (MBD2) FOR MEDULLOBLASTOMA THERAPY
Adhesion G-protein coupled receptors (ADGRs) are transmembrane proteins involved in cell-cell/matrix interactions. We found that the ADGRB1 gene, which encodes Brain-specific angiogenesis inhibitor 1 (BAI1), is epigenetically silenced in human medulloblastomas through a methyl-CpG binding protein 2...
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| Publicat a: | Neuro Oncol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216844/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1167 |
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