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CSIG-43. THE TYROSINE PHOSPHATASE PTPN12/PTP-PEST REGULATES PHOSPHORYLATION-DEPENDENT UBIQUITINATION AND STABILITY OF FOCAL ADHESION SUBSTRATES IN INVASIVE GLIOBLASTOMA CELLS
Glioblastoma (GBM) is an invasive brain cancer with tumor cells that disperse from the primary mass escaping surgical resection, displaying resistance to chemotherapy and radiation, and invariably giving rise to lethal recurrent lesions. Targeted therapies such as the anti-vascular endothelial growt...
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| Veröffentlicht in: | Neuro Oncol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216807/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.209 |
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