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CSIG-43. THE TYROSINE PHOSPHATASE PTPN12/PTP-PEST REGULATES PHOSPHORYLATION-DEPENDENT UBIQUITINATION AND STABILITY OF FOCAL ADHESION SUBSTRATES IN INVASIVE GLIOBLASTOMA CELLS

Glioblastoma (GBM) is an invasive brain cancer with tumor cells that disperse from the primary mass escaping surgical resection, displaying resistance to chemotherapy and radiation, and invariably giving rise to lethal recurrent lesions. Targeted therapies such as the anti-vascular endothelial growt...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: McCarty, Joseph, Morales, John, Guerrero, Paola, Chen, Zhihua
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216807/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.209
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