GENE-13. GENOMIC FUNCTIONAL ENHANCERS DEFINE POTENTIAL TUMORIGENESIS OF G-CIMP-LOW (IDH-MUTANT ASTROCYTOMA) TUMORS INDEPENDENT OF PROMOTER METHYLATION

Glioma CpG-island methylator phenotype (G-CIMP) is associated with IDH mutation and presents better clinical outcomes than for IDH wildtype gliomas. However, a recent stratification of G-CIMP tumors identified a subgroup of patients with distinct epigenetic changes in intergenic regions linked to po...

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Vydáno v:Neuro Oncol
Hlavní autoři: Sabedot, Thais, deCarvalho, Ana, Poisson, Laila, Snyder, James, Walbert, Tobias, Lee, Ian, Kalkanis, Steven, Berman, Benjamin, Noushmehr, Houtan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216556/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.439
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