GENE-07. GENOMIC ENHANCER METHYLATION IS ASSOCIATED WITH BIOLOGICAL AND CLINICAL FEATURES IN PITUITARY TUMORS

The importance of enhancers has been recently highlighted in a pan-can transcriptomic analysis that revealed causal interaction between active enhancers and actionable genes as well as their prognostic value. DNA methylation is associated with enhancer activity and its interplay with the transcripti...

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Publicat a:Neuro Oncol
Autors principals: Mosella, Maritza, Malta, Tathiane, Sabedot, Thais, Felicella, Michelle, Aho, Todd, Poisson, Laila, deCarvalho, Ana, Snyder, James, Lee, Ian, Kalkanis, Steven, Walbert, Tobias, Noushmehr, Houtan, Rock, Jack, Castro, Ana Valeria
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Abstracts
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216490/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.434
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