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OR24-5 Aberrant DNA Methylation in Regulatory Genomic Elements Are Associated with Invasive Behavior of Pituitary Macroadenomas: An Integrative Analysis of Epigenome-Wide Studies
A significant proportion of pituitary tumors (PT) invade adjacent structures. Few putative somatic mutations or copy number alterations have been associated with PT invasiveness. DNA methylation abnormalities in regulatory regions are known to impact gene expression and cancer behavior, but have not...
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| Publicat a: | J Endocr Soc |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Endocrine Society
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6554889/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR24-5 |
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