GENE-07. GENOMIC ENHANCER METHYLATION IS ASSOCIATED WITH BIOLOGICAL AND CLINICAL FEATURES IN PITUITARY TUMORS

The importance of enhancers has been recently highlighted in a pan-can transcriptomic analysis that revealed causal interaction between active enhancers and actionable genes as well as their prognostic value. DNA methylation is associated with enhancer activity and its interplay with the transcripti...

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Publicado en:Neuro Oncol
Main Authors: Mosella, Maritza, Malta, Tathiane, Sabedot, Thais, Felicella, Michelle, Aho, Todd, Poisson, Laila, deCarvalho, Ana, Snyder, James, Lee, Ian, Kalkanis, Steven, Walbert, Tobias, Noushmehr, Houtan, Rock, Jack, Castro, Ana Valeria
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216490/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.434
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