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GENE-13. GENOMIC FUNCTIONAL ENHANCERS DEFINE POTENTIAL TUMORIGENESIS OF G-CIMP-LOW (IDH-MUTANT ASTROCYTOMA) TUMORS INDEPENDENT OF PROMOTER METHYLATION
Glioma CpG-island methylator phenotype (G-CIMP) is associated with IDH mutation and presents better clinical outcomes than for IDH wildtype gliomas. However, a recent stratification of G-CIMP tumors identified a subgroup of patients with distinct epigenetic changes in intergenic regions linked to po...
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| Veröffentlicht in: | Neuro Oncol |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216556/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.439 |
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