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GENE-56. DEPLETION OF 5-HYDROXYMETHYLCYTOSINE IN AGGRESSIVE G-CIMP SUBTYPE
5-hydroxymethylcytosine (5hmC) is an oxidation product of 5-methylcytosine, a reaction potentially mediated by the Tet family of enzymes. Levels of 5hmC were reported to be lower in glioblastoma and because gliomas carrying an IDH1/2 mutation (high or low grade) manifest a CpG island methylator phen...
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| Udgivet i: | Neuro Oncol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692938/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.428 |
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