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TMOD-09. TARGETING THE PI3K-mTOR PATHWAY AND ELUCIDATING MECHANISMS OF RESISTANCE IN A NOVEL AND RELEVANT ANIMAL MODEL OF GLIOBLASTOMA

Pediatric glioblastoma (pGBM) and adult glioblastoma (aGBM), henceforth collectively referenced as GBM are incurable brain tumors with variable prognosis and response to treatments due to the intermolecular heterogeneity. In particular, the GBM MYCN subtype is a highly aggressive genetic group in bo...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Dey, Brittany, Wassell, Michelle, Perez, Jennifer, Stanton, Ann-Catherine, Mack, Stephen, Pollack, Ian, Agnihotri, Sameer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216540/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1122
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