Načítá se...
DDIS-22. WSD0922: A BBB PENETRABLE EGFR/EGFRVIII SMALL MOLECULE FOR THE TREATMENT OF GBM AND METASTATIC CNS TUMOR
Aberrant EGFR signaling caused by mechanisms of overexpression, mutation, or autocrine activation contributes for oncogenesis by inducing cell proliferation and resisting apoptosis. In patients with GBM, an overall frequency of 25–64% mutation is EGFRvIII (exon2-7 deletion). In patients with NSCLC h...
Uloženo v:
| Vydáno v: | Neuro Oncol |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2018
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216298/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.301 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|