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ANGI-10. WSD1227: A BRAIN PENETRABLE VEGFR2 INHIBITOR FOR THE TREATMENT OF PRIMARY AND METASTATIC BRAIN TUMORS

The VEGF pathway has emerged as an important target for cancer therapy by blocking the development of malignant neovasculature, thus to reduce oxygen availability to the tumor and decrease its growth. Anti-VEGF agents have been approved for several malignancies, such as GBM, NSCLC, mBC, CRC, OC, etc...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Zhang, Jinqiang, Zhong, Wei, Mu, Zhihua, Sun, Claire
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217140/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.111
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