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ANGI-10. WSD1227: A BRAIN PENETRABLE VEGFR2 INHIBITOR FOR THE TREATMENT OF PRIMARY AND METASTATIC BRAIN TUMORS

The VEGF pathway has emerged as an important target for cancer therapy by blocking the development of malignant neovasculature, thus to reduce oxygen availability to the tumor and decrease its growth. Anti-VEGF agents have been approved for several malignancies, such as GBM, NSCLC, mBC, CRC, OC, etc...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Zhang, Jinqiang, Zhong, Wei, Mu, Zhihua, Sun, Claire
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217140/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.111
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