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Effective CRISPR/Cas9-based nucleotide editing in zebrafish to model human genetic cardiovascular disorders

The zebrafish (Danio rerio) has become a popular vertebrate model organism to study organ formation and function due to its optical clarity and rapid embryonic development. The use of genetically modified zebrafish has also allowed identification of new putative therapeutic drugs. So far, most studi...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Tessadori, Federico, Roessler, Helen I., Savelberg, Sanne M. C., Chocron, Sonja, Kamel, Sarah M., Duran, Karen J., van Haelst, Mieke M., van Haaften, Gijs, Bakkers, Jeroen
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215435/
https://ncbi.nlm.nih.gov/pubmed/30355756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.035469
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