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Effective CRISPR/Cas9-based nucleotide editing in zebrafish to model human genetic cardiovascular disorders

The zebrafish (Danio rerio) has become a popular vertebrate model organism to study organ formation and function due to its optical clarity and rapid embryonic development. The use of genetically modified zebrafish has also allowed identification of new putative therapeutic drugs. So far, most studi...

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Détails bibliographiques
Publié dans:Dis Model Mech
Auteurs principaux: Tessadori, Federico, Roessler, Helen I., Savelberg, Sanne M. C., Chocron, Sonja, Kamel, Sarah M., Duran, Karen J., van Haelst, Mieke M., van Haaften, Gijs, Bakkers, Jeroen
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215435/
https://ncbi.nlm.nih.gov/pubmed/30355756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.035469
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