MicroRNA-96 Promotes Schistosomiasis Hepatic Fibrosis in Mice by Suppressing Smad7

Infection with Schistosoma causes aberrant expression of host microRNAs (miRNAs), and normalizing the levels of dysregulated miRNAs can attenuate pathology. Here, we show that the host miRNA, miR-96, is markedly upregulated during the progression of hepatic schistosomiasis. We demonstrate that eleva...

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Pubblicato in:Mol Ther Methods Clin Dev
Autori principali: Luo, Xufeng, Zhang, Dongmei, Xie, Jun, Su, Qin, He, Xing, Bai, Ruipu, Gao, Guangping, Pan, Weiqing
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214875/
https://ncbi.nlm.nih.gov/pubmed/30406154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.10.002
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