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MicroRNA-96 Promotes Schistosomiasis Hepatic Fibrosis in Mice by Suppressing Smad7

Infection with Schistosoma causes aberrant expression of host microRNAs (miRNAs), and normalizing the levels of dysregulated miRNAs can attenuate pathology. Here, we show that the host miRNA, miR-96, is markedly upregulated during the progression of hepatic schistosomiasis. We demonstrate that eleva...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Luo, Xufeng, Zhang, Dongmei, Xie, Jun, Su, Qin, He, Xing, Bai, Ruipu, Gao, Guangping, Pan, Weiqing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214875/
https://ncbi.nlm.nih.gov/pubmed/30406154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.10.002
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