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An enantioselective synthesis of the C(2)–C(16) segment of antitumor macrolide laulimalide(1)
An enantioselective synthesis of the C(2)–C(16) segment of the novel antitumor agent laulimalide is described. The key steps involve a highly diastereoselective allylation, ring-closing olefin metathesis of a homoallylic alcohol derived acrylate ester, a stereoselective anomeric alkylation and an el...
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| Publicado no: | Tetrahedron Lett |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6214628/ https://ncbi.nlm.nih.gov/pubmed/30393407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0040-4039(00)00158-1 |
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