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Synthetic studies of antitumor macrolide laulimalide: a stereoselective synthesis of the C(17)–C(28) segment
A stereoselective synthesis of the C(17)–C(28) segment of the potent antitumor macrolide, laulimalide has been accomplished. The key steps are a ring-closing olefin metathesis to construct the dihydropyran unit, nucleophilic addition of an alkynyl anion to the Weinreb amide, stereoselective reductio...
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| Publicado no: | Tetrahedron Lett |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217986/ https://ncbi.nlm.nih.gov/pubmed/30405275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0040-4039(00)00715-2 |
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