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An enantioselective synthesis of the C3–C21 segment of the macrolide immunosuppressive agent FR252921
An enantioselective synthesis of the C3–C21 segment of the novel immunosuppressant FR252921 is described. The C12 and C13 stereogenic centers were constructed by a non-aldol process utilizing optically active 4-phenylbutyrolactone. The C18 stereogenic center was installed using Braun's highly d...
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| Publicado no: | Tetrahedron Lett |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5094281/ https://ncbi.nlm.nih.gov/pubmed/27818534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2016.05.067 |
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