Synthetic Molecules for Disruption of the MYC Protein-Protein Interface

MYC is a key transcriptional regulator involved in cellular proliferation and has established roles in transcriptional elongation and initiation, microRNA regulation, apoptosis, and pluripotency. Despite this prevalence, functional chemical probes of MYC function at the protein level have been limit...

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Publicado en:Bioorg Med Chem
Autores principales: Jacob, Nicholas T, Miranda, Pedro O, Shirey, Ryan J, Gautam, Ritika, Zhou, Bin, de Orbe Izquierdo, M Elena, Hixon, Mark S, Hart, Jonathan R, Ueno, Lynn, Vogt, Peter K, Janda, Kim D
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214403/
https://ncbi.nlm.nih.gov/pubmed/30037753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2018.07.019
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