Synthetic Molecules for Disruption of the MYC Protein-Protein Interface

MYC is a key transcriptional regulator involved in cellular proliferation and has established roles in transcriptional elongation and initiation, microRNA regulation, apoptosis, and pluripotency. Despite this prevalence, functional chemical probes of MYC function at the protein level have been limit...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Jacob, Nicholas T, Miranda, Pedro O, Shirey, Ryan J, Gautam, Ritika, Zhou, Bin, de Orbe Izquierdo, M Elena, Hixon, Mark S, Hart, Jonathan R, Ueno, Lynn, Vogt, Peter K, Janda, Kim D
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214403/
https://ncbi.nlm.nih.gov/pubmed/30037753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2018.07.019
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