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A Structure- and Ligand-Based Virtual Screening of a Database of “Small” Marine Natural Products for the Identification of “Blue” Sigma-2 Receptor Ligands

Sigma receptors are a fascinating receptor protein class whose ligands are actually under clinical evaluation for the modulation of opioid analgesia and their use as positron emission tomography radiotracers. In particular, peculiar biological and therapeutic functions are associated with the sigma-...

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Bibliographic Details
Published in:Mar Drugs
Main Authors: Floresta, Giuseppe, Amata, Emanuele, Barbaraci, Carla, Gentile, Davide, Turnaturi, Rita, Marrazzo, Agostino, Rescifina, Antonio
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212963/
https://ncbi.nlm.nih.gov/pubmed/30322188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16100384
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