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Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands

Ibogaine is a psychoactive indole alkaloid with high affinity for several targets including the σ(2) receptor. Indeed, extensive data support the involvement of the σ(2) receptor in neurological disorders, including Alzheimer’s disease, schizophrenia, alcohol abuse and pain. Due to its serious side...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Floresta, Giuseppe, Dichiara, Maria, Gentile, Davide, Prezzavento, Orazio, Marrazzo, Agostino, Rescifina, Antonio, Amata, Emanuele
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386901/
https://ncbi.nlm.nih.gov/pubmed/30678129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030488
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