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A Structure- and Ligand-Based Virtual Screening of a Database of “Small” Marine Natural Products for the Identification of “Blue” Sigma-2 Receptor Ligands

Sigma receptors are a fascinating receptor protein class whose ligands are actually under clinical evaluation for the modulation of opioid analgesia and their use as positron emission tomography radiotracers. In particular, peculiar biological and therapeutic functions are associated with the sigma-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mar Drugs
Hauptverfasser: Floresta, Giuseppe, Amata, Emanuele, Barbaraci, Carla, Gentile, Davide, Turnaturi, Rita, Marrazzo, Agostino, Rescifina, Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212963/
https://ncbi.nlm.nih.gov/pubmed/30322188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16100384
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