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A Structure- and Ligand-Based Virtual Screening of a Database of “Small” Marine Natural Products for the Identification of “Blue” Sigma-2 Receptor Ligands

Sigma receptors are a fascinating receptor protein class whose ligands are actually under clinical evaluation for the modulation of opioid analgesia and their use as positron emission tomography radiotracers. In particular, peculiar biological and therapeutic functions are associated with the sigma-...

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Dettagli Bibliografici
Pubblicato in:Mar Drugs
Autori principali: Floresta, Giuseppe, Amata, Emanuele, Barbaraci, Carla, Gentile, Davide, Turnaturi, Rita, Marrazzo, Agostino, Rescifina, Antonio
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212963/
https://ncbi.nlm.nih.gov/pubmed/30322188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16100384
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