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Thioredoxin Confers Intrinsic Resistance to Cytostatic Drugs in Human Glioma Cells

Thioredoxin (Trx) overexpression is known to be a cause of chemotherapy resistance in various tumor entities. However, Trx effects on resistance are complex and depend strictly on tissue type. In the present study, we analyzed the impact of the Trx system on intrinsic chemoresistance of human gliobl...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Haas, Bodo, Schütte, Lena, Wos-Maganga, Maria, Weickhardt, Sandra, Timmer, Marco, Eckstein, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212897/
https://ncbi.nlm.nih.gov/pubmed/30248944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19102874
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