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Clinical pharmacology and regulatory consequences of GnRH analogues in prostate cancer
INTRODUCTION: GnRH (gonadotropin-releasing hormone) analogues are long-term known to be safe and effective in the clinical management of hormone-dependent advanced prostate cancer. However, their unusual mechanism of action of de-sensitizing pituitary receptors makes generic market entry challenging...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer Berlin Heidelberg
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4148177/ https://ncbi.nlm.nih.gov/pubmed/24756149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-014-1682-1 |
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