Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy mouse vessels

Vascular smooth muscle cells (VSMCs) show pronounced heterogeneity across and within vascular beds, with direct implications for their function in injury response and atherosclerosis. Here we combine single-cell transcriptomics with lineage tracing to examine VSMC heterogeneity in healthy mouse vess...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Dobnikar, Lina, Taylor, Annabel L., Chappell, Joel, Oldach, Phoebe, Harman, Jennifer L., Oerton, Erin, Dzierzak, Elaine, Bennett, Martin R., Spivakov, Mikhail, Jørgensen, Helle F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212435/
https://ncbi.nlm.nih.gov/pubmed/30385745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06891-x
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg