Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury

Accumulation of vascular smooth muscle cells (VSMCs) is a hallmark of multiple vascular pathologies, including following neointimal formation after injury and atherosclerosis. However, human VSMCs in advanced atherosclerotic lesions show reduced cell proliferation, extensive and persistent DNA damag...

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Udgivet i:Commun Biol
Main Authors: Uryga, Anna K., Grootaert, Mandy O. J., Garrido, Abel M., Oc, Sebnem, Foote, Kirsty, Chappell, Joel, Finigan, Alison, Rossiello, Francesca, d’Adda di Fagagna, Fabrizio, Aravani, Dimitra, Jorgensen, Helle F., Bennett, Martin R.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140103/
https://ncbi.nlm.nih.gov/pubmed/34021256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02123-z
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