Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy mouse vessels

Vascular smooth muscle cells (VSMCs) show pronounced heterogeneity across and within vascular beds, with direct implications for their function in injury response and atherosclerosis. Here we combine single-cell transcriptomics with lineage tracing to examine VSMC heterogeneity in healthy mouse vess...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Dobnikar, Lina, Taylor, Annabel L., Chappell, Joel, Oldach, Phoebe, Harman, Jennifer L., Oerton, Erin, Dzierzak, Elaine, Bennett, Martin R., Spivakov, Mikhail, Jørgensen, Helle F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212435/
https://ncbi.nlm.nih.gov/pubmed/30385745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06891-x
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