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Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy mouse vessels

Vascular smooth muscle cells (VSMCs) show pronounced heterogeneity across and within vascular beds, with direct implications for their function in injury response and atherosclerosis. Here we combine single-cell transcriptomics with lineage tracing to examine VSMC heterogeneity in healthy mouse vess...

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Publicat a:Nat Commun
Autors principals: Dobnikar, Lina, Taylor, Annabel L., Chappell, Joel, Oldach, Phoebe, Harman, Jennifer L., Oerton, Erin, Dzierzak, Elaine, Bennett, Martin R., Spivakov, Mikhail, Jørgensen, Helle F.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212435/
https://ncbi.nlm.nih.gov/pubmed/30385745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06891-x
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