CD11c-expressing Ly6C(+)CCR2(+) monocytes constitute a reservoir for efficient Leishmania proliferation and cell-to-cell transmission

The virulence of intracellular pathogens such as Leishmania major (L. major) relies largely on their ability to undergo cycles of replication within phagocytes, release, and uptake into new host cells. While all these steps are critical for successful establishment of infection, neither the cellular...

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Udgivet i:PLoS Pathog
Main Authors: Heyde, Sandrina, Philipsen, Lars, Formaglio, Pauline, Fu, Yan, Baars, Iris, Höbbel, Guido, Kleinholz, Corinna L., Seiß, Elena A., Stettin, Juliane, Gintschel, Patricia, Dudeck, Anne, Bousso, Philippe, Schraven, Burkhart, Müller, Andreas J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6211768/
https://ncbi.nlm.nih.gov/pubmed/30346994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007374
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