CCR2 Deficiency Impairs Ly6C(lo) and Ly6C(hi) Monocyte Responses in Orientia tsutsugamushi Infection

Orientia (O.) tsutsugamushi, the causative agent of scrub typhus, is a neglected, obligate intracellular bacterium that has a prominent tropism for monocytes and macrophages. Complications often involve the lung, where interstitial pneumonia is a typical finding. The severity of scrub typhus in huma...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Petermann, Michael, Orfanos, Zacharias, Sellau, Julie, Gharaibeh, Mohammad, Lotter, Hannelore, Fleischer, Bernhard, Keller, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287586/
https://ncbi.nlm.nih.gov/pubmed/34290699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.670219
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