CD11c-expressing Ly6C(+)CCR2(+) monocytes constitute a reservoir for efficient Leishmania proliferation and cell-to-cell transmission

The virulence of intracellular pathogens such as Leishmania major (L. major) relies largely on their ability to undergo cycles of replication within phagocytes, release, and uptake into new host cells. While all these steps are critical for successful establishment of infection, neither the cellular...

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Pubblicato in:PLoS Pathog
Autori principali: Heyde, Sandrina, Philipsen, Lars, Formaglio, Pauline, Fu, Yan, Baars, Iris, Höbbel, Guido, Kleinholz, Corinna L., Seiß, Elena A., Stettin, Juliane, Gintschel, Patricia, Dudeck, Anne, Bousso, Philippe, Schraven, Burkhart, Müller, Andreas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6211768/
https://ncbi.nlm.nih.gov/pubmed/30346994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007374
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