CD11c-expressing Ly6C(+)CCR2(+) monocytes constitute a reservoir for efficient Leishmania proliferation and cell-to-cell transmission

The virulence of intracellular pathogens such as Leishmania major (L. major) relies largely on their ability to undergo cycles of replication within phagocytes, release, and uptake into new host cells. While all these steps are critical for successful establishment of infection, neither the cellular...

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Vydáno v:PLoS Pathog
Hlavní autoři: Heyde, Sandrina, Philipsen, Lars, Formaglio, Pauline, Fu, Yan, Baars, Iris, Höbbel, Guido, Kleinholz, Corinna L., Seiß, Elena A., Stettin, Juliane, Gintschel, Patricia, Dudeck, Anne, Bousso, Philippe, Schraven, Burkhart, Müller, Andreas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6211768/
https://ncbi.nlm.nih.gov/pubmed/30346994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007374
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