Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages

Pancreatic ductal adenocarcinoma (PDAC) tumor growth is enhanced by tumor-associated macrophages (TAMs), yet the mechanisms by which tumor cells and TAMs communicate are not fully understood. Here we show that exosomes secreted by PDAC cell lines differed in their surface proteins, lipid composition...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Linton, Samuel S., Abraham, Thomas, Liao, Jason, Clawson, Gary A., Butler, Peter J., Fox, Todd, Kester, Mark, Matters, Gail L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6211741/
https://ncbi.nlm.nih.gov/pubmed/30383833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206759
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