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Remarkably Robust Antiviral Immune Response Despite Combined Deficiency in Caspase-8 and RIPK3
Caspase-8 (Casp8)-mediated signaling triggers extrinsic apoptosis while suppressing receptor interacting protein kinase (RIPK)3-dependent necroptosis. Even though Casp8 is dispensable for the development of innate and adaptive immune compartments in mice, the importance of this proapoptotic protease...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6211196/ https://ncbi.nlm.nih.gov/pubmed/30194111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800110 |
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