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Caspase-8 restricts antiviral CD8 T cell hyperaccumulation

The magnitude of CD8 T cell responses against viruses is checked by the balance of proliferation and death. Caspase-8 (CASP8) has the potential to influence response characteristics through initiation of apoptosis, suppression of necroptosis, and modulation of cell death-independent signal transduct...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Feng, Yanjun, Daley-Bauer, Lisa P., Roback, Linda, Guo, Hongyan, Koehler, Heather S., Potempa, Marc, Lanier, Lewis L., Mocarski, Edward S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660791/
https://ncbi.nlm.nih.gov/pubmed/31285326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904319116
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