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RIP3 mediates the embryonic lethality of caspase-8-deficient mice
Apoptosis and necroptosis are complementary pathways controlled by common signaling adaptors, kinases and proteases; among these, caspase-8 (Casp8) is critical for death receptor (DR)-induced apoptosis. This caspase has also been implicated in nonapoptotic pathways that regulate Fas-associated via d...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060292/ https://ncbi.nlm.nih.gov/pubmed/21368762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09857 |
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