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Caspase-8 deficiency in T cells leads to a lethal lymphoinfiltrative immune disorder
Caspase-8 is best known for its cell death function via death receptors. Recent evidence indicates that caspase-8 also has nonapoptotic functions. Caspase-8 deficiency is associated with pathologies that are unexpected for a proapoptotic molecule, such as abrogation of activation-induced lymphocyte...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212954/ https://ncbi.nlm.nih.gov/pubmed/16157684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050683 |
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