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Caspase-8 deficiency in T cells leads to a lethal lymphoinfiltrative immune disorder

Caspase-8 is best known for its cell death function via death receptors. Recent evidence indicates that caspase-8 also has nonapoptotic functions. Caspase-8 deficiency is associated with pathologies that are unexpected for a proapoptotic molecule, such as abrogation of activation-induced lymphocyte...

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Bibliografische gegevens
Hoofdauteurs: Salmena, Leonardo, Hakem, Razqallah
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212954/
https://ncbi.nlm.nih.gov/pubmed/16157684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050683
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