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Functions of neutral ceramidase in the Golgi apparatus

Ceramidases hydrolyze ceramides into sphingosine and fatty acids, with sphingosine being further metabolized into sphingosine-1-phosphate (S1P); thus, ceramidases control the levels of these bioactive sphingolipids in cells and tissues. Neutral ceramidase (nCDase) is highly expressed in colorectal t...

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Bibliografiske detaljer
Udgivet i:J Lipid Res
Main Authors: Sakamoto, Wataru, Coant, Nicolas, Canals, Daniel, Obeid, Lina M., Hannun, Yusuf A.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6210901/
https://ncbi.nlm.nih.gov/pubmed/30154232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M088187
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