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A Novel Role for the Interleukin-1 Receptor Axis in Resistance to Anti-EGFR Therapy

Cetuximab (CTX) is a monoclonal antibody targeting the epidermal growth factor receptor (EGFR), commonly used to treat patients with metastatic colorectal cancer (mCRC). Unfortunately, objective remissions occur only in a minority of patients and are of short duration, with a population of cells sur...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Gelfo, Valerio, Mazzeschi, Martina, Grilli, Giada, Lindzen, Moshit, Santi, Spartaco, D’Uva, Gabriele, Győrffy, Balázs, Ardizzoni, Andrea, Yarden, Yosef, Lauriola, Mattia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6210663/
https://ncbi.nlm.nih.gov/pubmed/30261609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10100355
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